A regional reflection: The Dutch High Tech and Semiconductor region in the Brainport Eindhoven is responsible for approximately 40% of all patents in the Netherlands. Patents, one of the innovation parameters, show us that the Dutch are an innovation powerhouse in hardware innovation. Two (of the many) reasons are the presence of strong campuses like the High-Tech campus, the Eindhoven University of Technology, Brainport industry campus, Helmond Automotive campus amongst others. The campuses shape a unique start- and scale up climate that fits Brabant’s entrepreneurship. Another reason is the presence of global (often Dutch found and hardware-oriented) companies like ASML, NXP Semiconductors, Vanderlande, VDL group, Signify (previously Philips Lightning, Philips Royal amongst others.